21 panel cups
Compare 21 Panel Drug Test Cups
A 21 panel drug test cup, also called a 21 panel urine drug test, combines specimen collection and preliminary screening for 21 drugs or drug classes in one Serenity cup. Beyond the standard drugs of abuse, it screens for substances increasingly found in the illicit supply, such as fentanyl, xylazine, kratom, K2, psilocybin and the alcohol metabolite EtG, with additional specialty panels depending on the configuration.
This category includes three Forensic Use Only configurations, each with specimen-validity (ADLTX) indicators and a temperature strip. Two share the same 20 drug panels, with one adding tianeptine (ZAZA); the third adds DXM, gabapentin, LSD and 6-MAM with lower stimulant and fentanyl cutoffs. Tiered bulk pricing is available, and qualifying orders of 100 or more cups ship free the same day.
Use the comparison below to choose the 21 panel drug screen that matches your program’s testing requirements.
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21 panel drug test with DXM
21 Panel Drug Test Cup – DXM, GAB, LSD, 6-MAM & ADLTX
6-MAM, ADLTX, AMP, BUP, BZO, COC, DXM, EtG, FEN, GAB, K2/Spice, KRA, LSD, MET, Methadone (MTD), OPI/MOR, OXY, PCP, THC, PSY, XYL, ZAZA As Low As $2.59 BUY NOW
21 Panel Drug Screen Cup – PSY, XYL, FEN, EtG & ADLTX
ADLTX, AMP, BAR, BUP, BZO, COC, EtG, FEN, K2/Spice, KET, KRA, MDMA, MET, Methadone (MTD), OPI/MOR, OXY, PCP, THC, PSY, TRA, XYL As Low As $2.59 BUY NOW
21 Panel Drug Test Cup – ZAZA, XYL, PSY & ADLTX
ADLTX, AMP, BAR, BUP, BZO, COC, EtG, FEN, K2/Spice, KET, KRA, MDMA, MET, Methadone (MTD), OPI/MOR, OXY, PCP, THC, PSY, TRA, XYL, ZAZA As Low As $2.59 BUY NOWChoose a 21 Panel Drug Test by Configuration
| Product | Key configuration | Main difference |
|---|---|---|
| 21 Panel Drug Screen Cup – PSY, XYL, FEN, EtG & ADLTX | PSY/500, XYL/1000, FEN/20 and pH, SG, CR | 20 drug panels with specimen-validity indicators |
| 21 Panel Drug Test Cup – ZAZA, XYL, PSY & ADLTX | ZAZA/500, PSY/500, XYL/1000 and pH, SG, CR | Adds a tianeptine (ZAZA) panel to the same 20 drug panels |
| 21 Panel Drug Test Cup – DXM, GAB, LSD, 6-MAM & ADLTX | DXM/100, GAB/1000, LSD/50, 6-MAM/10, ZAZA/500, FEN/10 and pH, SG, CR | Adds DXM, gabapentin, LSD and 6-MAM with lower AMP, MET, COC and FEN cutoffs; no BAR, MDMA, KET or TRA |
Drug panels shared by the PSY/XYL and ZAZA cups: AMP/1000, BAR/300, BUP/10, BZO/300, COC/300, EtG/300, FEN/20, K2/50, KET/1000, KRA/500, MDMA/500, MET/1000, MTD/300, OPI/300, OXY/100, PCP/25, PSY/500, THC/50, TRA/100 and XYL/1000.
How to Select the Right 21 Panel Drug Test
Verify the exact panel configuration
Two products marketed as a 21 panel drug test may screen for different substances. Suppliers commonly vary the last several assays, using tianeptine, gabapentin, LSD, dextromethorphan or 6-MAM depending on the configuration. Always review the complete drug and cutoff table on the product page before ordering.
Confirm the intended-use classification
All 21 panel cups in this category are labeled Forensic Use Only. They are intended for courts, law-enforcement agencies, probation and parole offices, correctional facilities and laboratories performing testing for these entities.
Forensic Use Only products are not CLIA waived or FDA cleared and should not be marketed for personal home testing or routine clinical use. Clinical buyers should review our CLIA-waived drug test cups guide.
Compare neighboring panel counts
If your program needs additional coverage, compare the 22 panel drug test cups with nitazene screening or the 24 panel and 28 panel configurations. Programs that do not require xylazine or psilocybin screening may find a 20 panel drug test cup more economical.
Understand specimen-validity indicators
All three 21 panel cups include pH, specific gravity and creatinine indicators, commonly identified as ADLTX, plus a temperature strip. These indicators provide information used when assessing specimen validity. They are not drug-screening panels and are not counted in the 21 panel total.
Understanding Preliminary Results
Rapid urine cups provide preliminary screening results. For an individual assay, two visible lines generally indicate a negative result, including when the test line is faint. A visible control line without the corresponding test line indicates a preliminary non-negative result. If the control line does not appear, the assay is invalid.
Always follow the exact instructions and reading window supplied with the selected product. Preliminary non-negative results should be confirmed by a certified laboratory using GC/MS or LC-MS/MS before a final decision is made.
For illustrated interpretation guidance, review how to read a drug test cup. Buyers comparing screening thresholds can also review our guide to drug test cutoff levels.
Bulk 21 Panel Drug Tests
DrugTestingCup offers tiered pricing on all three 21 panel drug test cup configurations. Quantity pricing is displayed after the buyer selects the cup option on the individual product page. Qualifying orders of 100 or more cups receive free shipping under the current website offer.
Before placing a large order, verify the panel configuration, cutoff levels, intended-use classification and current availability. Agencies and distributors planning recurring or multi-site purchases can review our wholesale drug testing supplies options.
21 Panel Drug Test Guides
Before selecting a configuration, review our 21 panel drug test list to see what each panel screens for and how 21 panel configurations differ.
Buyers planning test schedules can use our guide to urine drug test detection windows and the dedicated overview of fentanyl detection windows.
Substance-specific resources explain dextromethorphan (DXM), LSD on a drug test, tianeptine (ZAZA), kratom, nitazenes, medetomidine (rhino tranq) and adulterants and specimen-validity indicators.
Frequently Asked Questions
What does a 21 panel drug test detect?
The PSY/XYL and ZAZA cups screen for AMP, BAR, BUP, BZO, COC, EtG, FEN, K2, KET, KRA, MDMA, MET, MTD, OPI, OXY, PCP, PSY, THC, TRA and XYL, and the ZAZA cup adds tianeptine. The DXM cup screens for AMP, BUP, BZO, COC, MET, MTD, OPI, OXY, THC, PCP, DXM, K2, KRA, EtG, FEN, GAB, LSD, 6-MAM, ZAZA, XYL and PSY. Check the individual product table before ordering.
What is the difference between the 21 panel cups?
The PSY/XYL and ZAZA cups share the same 20 drug panels and ADLTX indicators. The ZAZA cup adds a tianeptine (ZAZA) panel at 500 ng/mL for programs that monitor that substance.
Are 21 panel drug test cups CLIA waived?
No. All products in this category are labeled Forensic Use Only. The intended-use classification must be verified on the exact product page and packaging.
Does a 21 panel drug test detect fentanyl and xylazine?
Yes. All three configurations include a dedicated fentanyl panel (FEN/20, or FEN/10 on the DXM cup) and a xylazine panel at 1,000 ng/mL. A standard opiate panel alone does not screen for fentanyl.
Which 21 panel cup includes LSD, DXM or 6-MAM?
Only the 21 panel drug test with DXM, gabapentin, LSD and 6-MAM includes those panels. It also uses lower AMP/500, MET/500, COC/150 and FEN/10 cutoffs.
Do ADLTX indicators count as drug panels?
No. The pH, specific gravity and creatinine indicators provide specimen-validity information. They are separate from the drug-screening assays.
Can a 21 panel cup be used for DOT drug testing?
No. DOT-regulated drug tests must be performed by a certified laboratory. Rapid cups are used in non-DOT programs.
What should be done with a preliminary non-negative result?
A preliminary non-negative result should be confirmed by a certified laboratory using GC/MS or LC-MS/MS when required by the testing program, applicable rules or the consequences of the decision.
Can 21 panel drug tests be purchased in bulk?
Yes. Individual product pages display tiered quantity pricing, and qualifying orders of 100 or more cups receive free shipping under the current website offer.
