21 Panel Drug Screen Cup – PSY, XYL, FEN, EtG & ADLTX

21 Panel Drug Screen Cup – PSY, XYL, FEN, EtG & ADLTX

The 21 panel drug screen cup combines urine specimen collection, 20 preliminary drug-screening assays and three specimen-validity indicators in one integrated 120 mL Serenity cup. It pairs broad conventional drug screening with specialty panels for fentanyl, xylazine, psilocybin, kratom, K2, ketamine, tramadol and EtG.

Products sold with the same overall panel count do not always screen for the same substances. This configuration contains 20 drug and metabolite targets plus separate pH, specific gravity and creatinine indicators. The ADLTX checks are not counted as drug panels and are interpreted separately from the screening result lines.

The specialty configuration includes XYL/1000, PSY/500, FEN/20, K2/50, KRA/500, KET/1000, TRA/100 and ETG/300. Each is a dedicated assay rather than an assumed part of a conventional drug class — fentanyl and tramadol, for example, are screened separately from the OPI/300 panel.

The cup also covers commonly requested drug classes including AMP, BAR, BUP, BZO, COC, MDMA, MET, MTD, OPI, OXY, PCP and THC.

This product is supplied as a Forensic Use Only configuration. Buyers who also need tianeptine screening can compare the 21 panel drug test cup with ZAZA. Programs that need DXM, gabapentin, LSD or 6-MAM screening can compare the 21 panel drug test with DXM, gabapentin, LSD and 6-MAM.

21 Panel Drug Screen List and Cutoff Levels

The complete configuration is shown below. Compare both the analytes and cutoff concentrations, because different 21 panel products can have substantially different screening profiles.

Additional specimen-validity indicators: pH, specific gravity (SG) and creatinine (CR).

Cutoff levels are those printed for this configuration. For thresholds across other products, see our guide to drug test cutoff levels.

120 mL 21 Panel Drug Screen Cup Features

The integrated 120 mL Serenity cup combines specimen collection and multi-panel screening in one device. Urine is collected directly into the cup, so there is no need to transfer the specimen to separate dip cards or cassettes during initial screening.

All 20 screening assays are built into the device, along with three specimen-validity indicators. A built-in temperature strip provides an additional specimen reference shortly after collection when read according to the manufacturer’s instructions.

The leak-resistant click-top lid supports cleaner handling, and the single-device format reduces the number of separate tests a collector has to manage per donor.

Buyers comparing configurations can review the 21 panel drug test cup with ZAZA and xylazine, or view all 21 panel drug test cups.

Fentanyl, Xylazine, Psilocybin, Kratom & K2 Screening

The specialty-panel combination is what separates this cup from smaller panel counts and from other expanded configurations.

FEN/20 provides dedicated preliminary fentanyl screening separate from the OPI/300 panel, while XYL/1000 screens for xylazine, a veterinary sedative the CDC reports is increasingly found in the illegal drug supply.

PSY/500 screens for psilocybin, KRA/500 provides kratom-related screening and K2/50 covers synthetic cannabinoids. A standard THC panel does not screen for K2.

KET/1000 is a dedicated ketamine assay, TRA/100 screens for tramadol, and ETG/300 screens for ethyl glucuronide, an alcohol metabolite. EtG results do not measure blood alcohol concentration or current impairment.

How to Read the Screening Results

Interpret each drug assay individually within the manufacturer’s specified reading window.

• Negative: Both the control line and test line appear. A faint visible test line is still read as negative.
• Non-negative / presumptive positive: The control line appears, but the test line is absent.
• Invalid: The control line is absent, regardless of whether a test line appears. Repeat the test with a new cup.

A non-negative result is preliminary. Confirm it with a certified laboratory using GC/MS or LC-MS/MS before making a final decision.

Read the ADLTX indicators separately using the supplied color chart. For a general explanation of line-based results, see how to read a drug test cup.

Who Uses This Forensic Screening Configuration?

This 21 panel drug screen cup is designated Forensic Use Only. Appropriate users include law-enforcement-related testing programs such as:

• Court systems, drug courts and police departments
• Probation, parole and pretrial services offices
• Prisons, jails and correctional facilities
• Laboratories performing forensic testing for those entities

Select the configuration according to the required drug menu, collection procedures and intended testing purpose. Product labeling and the manufacturer’s instructions determine suitability for a particular use.

Review our Forensic Use Only policy and customer acknowledgement before purchasing.

Forensic Use Only

This 21 panel drug screen cup is labeled Forensic Use Only. It is not CLIA waived or FDA cleared and should be selected, used and interpreted according to its current labeling, package insert and intended-use designation.

Forensic Use Only status is different from CLIA-waived status and does not transfer between products with similar panel counts. Clinical buyers should review our CLIA-waived drug test cups guide. Rapid cups are also not used for DOT-regulated testing, which requires a certified laboratory.

Bulk & Wholesale 21 Panel Drug Test Cups

DrugTestingCup.com offers this 21 panel drug screen cup with quantity-based pricing for agencies and distributors buying expanded urine screening in volume. Tiered pricing is shown after you select the cup option above.

FREE SHIPPING is available on qualifying orders of 100 cups or more, and orders placed before 3:00 PM EST ship the same business day. For recurring, multi-site or distributor orders, visit our wholesale drug testing supplies page or contact info@drugtestingcup.com.

Frequently Asked Questions

What does this 21 panel drug screen cup test for?

This configuration includes AMP/1000, BAR/300, BUP/10, BZO/300, COC/300, MDMA/500, MET/1000, MTD/300, OPI/300, OXY/100, PCP/25, THC/50, ETG/300, FEN/20, K2/50, KET/1000, KRA/500, TRA/100, XYL/1000 and PSY/500, plus pH, specific gravity and creatinine specimen-validity indicators.

How is this cup different from the 21 panel cup with ZAZA?

Both cups share the same 20 drug panels and ADLTX indicators. The ZAZA configuration adds a tianeptine (ZAZA) panel at 500 ng/mL. Choose the ZAZA cup if your program monitors tianeptine.

Does this 21 panel drug screen include fentanyl?

Yes. It contains a dedicated FEN/20 panel. Fentanyl is screened separately from the OPI/300 opiate panel.

Does this drug screen include xylazine and psilocybin?

Yes. The cup includes a XYL/1000 xylazine panel and a PSY/500 psilocybin panel.

Does this drug screen include EtG?

Yes. ETG/300 screens for ethyl glucuronide, an alcohol metabolite. It does not measure blood alcohol concentration or current impairment.

Does KRA mean K2 or synthetic marijuana?

No. KRA is the kratom panel. Synthetic cannabinoids are screened on the separate K2/50 panel.

What are the three ADLTX indicators?

The ADLTX indicators are pH, specific gravity and creatinine. They provide specimen-validity information and are not counted as drug panels.

Is this 21 panel drug screen cup CLIA waived?

No. This configuration is labeled Forensic Use Only. It is intended for courts, law-enforcement agencies, probation and parole offices, correctional facilities and laboratories testing for these entities.

Can this cup be used for DOT drug testing?

No. DOT-regulated drug tests must be performed by a certified laboratory. Rapid cups are used in non-DOT programs.

Can this 21 panel drug screen cup be purchased in bulk?

Yes. Quantity pricing is available, qualifying orders of 100 cups or more receive free shipping, and larger recurring or distributor orders may qualify for additional wholesale pricing.