28 Panel Drug Test Cup with Medetomidine, Nitazene & Xylazine

28 Panel Drug Test Cup with Medetomidine, Nitazene and Xylazine

This 28 panel drug test with medetomidine is an expanded urine screening cup designed for programs that need specialty targets beyond a traditional 5-panel, 10-panel or 12-panel test. The ULTRA Cup combines urine collection, preliminary qualitative screening and three specimen-validity indicators in one device.

The configuration includes several emerging-drug targets that require dedicated assays, including MED/1000 medetomidine, NTZ/2000 Nitazene and XYL/1000 xylazine. It also includes separate screening for FEN/20 fentanyl, ZAZA/500 tianeptine, D8/25, KRA/500 kratom, K2/50 synthetic cannabinoids, KET/1000 ketamine, PSY/500 psilocybin and LSD/50.

Traditional drug and drug-class screening is also included for amphetamines, barbiturates, buprenorphine, benzodiazepines, cocaine, MDMA, methamphetamine, methylphenidate, methadone, opiates, oxycodone, PCP, TCA, THC, tramadol and EtG.

This expanded combination makes the product different from our other 28 panel drug test, which uses a different specialty-panel configuration. Buyers should compare the complete panel list rather than assuming two 28-panel cups are interchangeable.

This product is labeled Forensic Use Only. Always review the current product label and package insert before purchase or use.

Why This 28 Panel Drug Test Configuration Is Different

The number of panels alone does not tell you what a drug test can screen for. A standard multi-panel cup may cover THC, cocaine, amphetamines, opiates and benzodiazepines while leaving out newer or less commonly screened substances.

This 28 panel drug test cup places a much greater emphasis on emerging-drug coverage. Medetomidine, Nitazene and xylazine are separate targets. Fentanyl is also screened independently instead of being treated as part of a general opiate panel.

Other specialty assays in the same cup cover tianeptine/ZAZA, Delta-8, kratom, synthetic cannabinoids/K2, ketamine, psilocybin and LSD. These targets are not interchangeable, and a negative result on one panel should never be treated as the result for another.

This is especially important when comparing this product with our 24 panel drug test cup or the other 28 panel ULTRA configuration. The products overlap on many standard drugs, but their specialty panels differ.

Drug Panels and Cutoff Levels

The current live product configuration lists the following analytes and cutoff concentrations. Because expanded configurations can change between production lots, verify the current package insert before placing a large repeat order.

Cutoff concentrations are screening thresholds. They do not show the exact amount of a substance present, the exact time of exposure or current impairment. Review our drug test cutoff level guide for more information about how cutoff levels are used in rapid urine screening.

Medetomidine, Nitazene and Xylazine Screening

The main SEO and product difference on this page is the combination of medetomidine, Nitazene and xylazine in the same expanded urine screening cup.

Medetomidine is a sedative that requires a dedicated MED assay. It should not be confused with xylazine simply because both substances may be described in public-health discussions involving the illicit opioid supply. The U.S. Centers for Disease Control and Prevention reported in 2026 that medetomidine has been detected in the U.S. illegal drug supply, primarily in mixtures containing illegally manufactured fentanyl.

For a detailed explanation of this emerging target, read our Medetomidine and “Rhino Tranq” guide.

This cup also includes XYL/1000 for xylazine. XYL and MED are different assays and should be interpreted separately. If your testing program requires only xylazine screening rather than a large multi-panel configuration, compare our Xylazine Drug Test Kit.

Nitazenes are a separate group of synthetic opioids. They should not be confused with nitrazepam, nor should the NTZ panel be treated as the same test as fentanyl or a conventional OPI assay. The DEA identifies nitazenes as benzimidazole synthetic opioids and has reported them in mixtures containing fentanyl and other illicit substances.

This 28-panel configuration uses NTZ/2000. DrugTestingCup.com also offers a targeted Nitazene Drug Test Strip when a single-panel NTZ screen is more appropriate than a large multi-panel cup.

The DEA’s 2026 public safety advisory specifically discusses fentanyl appearing with emerging substances including xylazine, nitazenes and medetomidine. This is one reason these analytes should be treated as separate screening targets rather than grouped under one general opioid result.

Fentanyl, Opiates and Specialty Opioid-Related Panels

This 28 panel drug test cup with Nitazene includes several opioid-related assays, but each has its own screening target.

The cup includes:

• FEN/20 for fentanyl
• NTZ/2000 for the listed Nitazene assay
• OPI/300 for the broader opiate panel
• OXY/100 for oxycodone
• BUP/10 for buprenorphine
• MTD/300 for methadone
• TRA/100 for tramadol

One result should not automatically be used to interpret another. A conventional opiate assay does not mean the device will detect every synthetic opioid, and a dedicated fentanyl panel does not automatically provide Nitazene screening.

This is one of the strongest reasons to compare the full analyte list before buying an expanded multi-panel test. A product described only as a “28 panel drug test” does not tell you which opioid-related specialty assays are included.

ZAZA, Delta-8, Kratom, K2 and Other Specialty Panels

The cup also provides broader coverage outside traditional opioid screening.

ZAZA/500 is included for the listed tianeptine-related target. Tianeptine requires a dedicated assay and should not be assumed to appear under the TCA, opioid or benzodiazepine panels simply because of its pharmacologic or product associations.

The configuration includes both a conventional THC/50 panel and a separate D8/25 low-cutoff cannabinoid configuration. These results should be read independently according to the manufacturer documentation.

K2/50 adds a separate synthetic-cannabinoid screening target. A standard THC panel should not automatically be expected to provide the same screening coverage as a dedicated K2/Spice assay.

KRA/500 provides kratom-related screening. Kratom assays can differ in the compounds they recognize, so a KRA result should not automatically be described as a dedicated 7-hydroxymitragynine result unless the manufacturer’s cross-reactivity documentation supports that statement. Our Kratom vs. 7-OH drug testing guide explains why this distinction matters.

Other specialty screening targets include KET/1000 ketamine, PSY/500 psilocybin, LSD/50 and MPH/1000 methylphenidate. These dedicated panels expand the testing profile beyond the substances normally included in smaller multi-panel cups.

Choosing Between the Two 28 Panel Drug Test Cups

DrugTestingCup.com carries more than one 28-panel configuration. This is important for both buyers and search engines because the two product pages should not be treated as duplicates.

This product is the better configuration to review when you specifically need:

• MED/1000 Medetomidine
• NTZ/2000 Nitazene
• XYL/1000 Xylazine
• FEN/20 Fentanyl
• ZAZA/500 Tianeptine
• D8/25
• KRA/500 Kratom
• K2/50
• KET/1000

The other 28 panel ULTRA drug test uses a different expanded panel combination and should remain the primary product page for the broader generic search term 28 panel drug test.

Buyers who do not need as many specialty targets can also compare the 24 panel drug test cup with MED, Nitazene and XYL.

This comparison approach helps avoid ordering the wrong cup simply because two products share the same total panel count.

How to Use and Read the 28 Panel Drug Test Cup

Before collection, verify the expiration date and make sure the device packaging is intact. Review the current product insert before opening the cup. The manufacturer instructions supplied with the current lot take priority over general website guidance.

Collect urine directly into the cup, secure the lid and keep the device upright on a clean, flat surface. Check the temperature indicator and specimen-validity results during the time period specified in the instructions. Allow the individual drug-test strips to develop and read the results only during the stated reading window.

• Negative: both the Control line and Test line appear for the individual panel.
• Preliminary non-negative: the Control line appears but the Test line is absent for that panel.
• Invalid: the required Control line does not appear. Do not interpret the affected panel and repeat the test according to the supplied instructions.

A faint Test line should be interpreted according to the manufacturer’s instructions. The darkness of the line should not be used to estimate drug concentration.

The FDA explains that rapid drugs-of-abuse tests provide qualitative screening results. A preliminary positive or non-negative result may require a more specific laboratory method for confirmation.

A negative result also does not prove that no exposure occurred. The analyte may be below the cutoff, the wrong target may have been tested, or collection may have occurred outside the period when the substance or metabolite was detectable.

Built-In Adulteration Checks

The 28 panel drug test cup includes ADLTX adulteration testing for:

• Specific Gravity
• pH
• Creatinine

These specimen validity checks help identify urine samples that may be diluted, substituted, or outside expected validity ranges. This is especially important for professional testing programs where sample integrity matters.

By combining drug screening and specimen validity checks in one cup, facilities can simplify the testing process and reduce the need for separate adulteration strips.

Product Summary

The 28 Panel Drug Test Cup with ADLTX adulteration checks is built for organizations that need expanded urine drug screening in one device.

With detection for traditional substances, prescription medications, synthetic drugs, alcohol metabolites, and emerging drug panels such as Medetomidine, Nitazenes, Xylazine, Psilocybin, LSD, Delta-8 THC, ZAZA, Ketamine, Kratom, K2, and Fentanyl, this cup offers one of the broadest screening profiles available.

For rehabilitation centers, employers, healthcare providers, and correctional facilities, this expanded panel provides a practical, efficient, and professional testing solution.

Why Choose DrugTestingCup.com?

We are a trusted supplier for wholesale drug testing cups and multi-panel screening solutions across the U.S. Our platform is designed for:

• Competitive bulk pricing
• Fast nationwide fulfillment
• B2B-friendly ordering
• Reliable compliance-grade products
• Dedicated customer support for enterprise and government buyers

Frequently Asked Questions

What makes this 28 panel drug test different?

This configuration is built around expanded screening for emerging and specialty targets, including MED/1000 medetomidine, NTZ/2000 Nitazene, XYL/1000 xylazine, FEN/20 fentanyl, ZAZA/500, D8/25, KRA/500, K2/50 and KET/1000.

Does this 28 panel drug test include medetomidine?

Yes. This configuration includes a dedicated MED/1000 medetomidine screening panel.

Does the cup include Nitazene?

Yes. The current configuration lists NTZ/2000. Nitazene screening should be interpreted separately from fentanyl and conventional opiate results.

Does this test include xylazine?

Yes. It includes a dedicated XYL/1000 xylazine screening panel.

Does it test for fentanyl?

Yes. It includes FEN/20 for fentanyl screening. FEN, NTZ and OPI are separate result areas.

Does this product test for tianeptine or ZAZA?

Yes. The configuration includes ZAZA/500 for the listed tianeptine-related screening target.

Does the cup include Delta-8 and THC?

Yes. The current configuration lists D8/25 and THC/50 as separate screening targets.

Does it test for kratom?

Yes. It includes KRA/500. Review the manufacturer’s assay documentation for the exact target compounds and cross-reactivity profile.

Does this product include K2?

Yes. K2/50 provides a separate synthetic-cannabinoid screening target from the conventional THC panel.

What are the three ADLTX checks?

The product includes Specific Gravity, pH and Creatinine specimen-validity indicators. These are not additional drug panels.

Are the two 28 panel products on DrugTestingCup.com the same?

No. They contain different specialty-panel combinations. This URL should be selected when MED, NTZ and XYL are key requirements. Always compare the complete analyte list before ordering.

Is this 28 panel drug test CLIA waived?

No. This specific expanded configuration is labeled Forensic Use Only.

Are preliminary non-negative results final?

No. Rapid urine drug screening provides preliminary qualitative results. Appropriate laboratory confirmation should be used when required.

Can this 28 panel drug test be purchased in bulk?

Yes. Quantity pricing is available, with free shipping on qualifying purchases of 100 cups or more.