OPI 300 vs OPI 2000 describes a difference in the listed opiate screening cutoff: 300 ng/mL versus 2000 ng/mL. The numbers identify assay thresholds, not the number of drugs tested, a measured result or a detection period.
This distinction matters when comparing 10 panel drug test cups. Two models can contain the same drug-class panels while using different thresholds for the opiate assay.
OPI 300 vs OPI 2000?
| Label | Listed Cutoff | Meaning |
|---|---|---|
| OPI/300 | 300 ng/mL | Opiate screening at the lower of these two thresholds. |
| OPI/2000 | 2000 ng/mL | Opiate screening at the higher threshold. |
OPI commonly identifies an opiate assay. Manufacturer documentation may describe its calibration using morphine. The exact substances recognized by an assay and their relative responses depend on the device’s design and cross-reactivity data.
The printed cutoff is therefore not a promise that every opioid will produce the same response at that concentration. Read the matching insert when a particular drug or metabolite is important.
What Changes When the Cutoff Is Higher?
A lower threshold is intended to flag lower concentrations of the assay’s target than a higher threshold, when comparing otherwise suitable methods. This can change screening classification near the thresholds, but an individual result also depends on the assay and specimen.
Neither number establishes overall test accuracy or makes one configuration suitable for every program. A test must match the required analytes, decision thresholds and intended use. The cutoff also does not tell you how long a substance will remain detectable in a particular person.
Compare Two 120ml Serenity Cup Configurations
These two ten-panel cups provide a useful product comparison because their other nine listed assays and cutoffs match.
| Product | Product Code | Opiate Cutoff |
|---|---|---|
| 120ml MDMA and buprenorphine cup | SM-CDOA-4105 | 300 ng/mL |
| 120ml MDMA cup with OPI2000 | SM-CDOA-8104 | 2000 ng/mL |
Both list AMP/1000, BUP/10, BZO/300, COC/300, MDMA/500, MET/1000, MTD/300, OXY/100 and THC/50 alongside the opiate assay. Their different OPI thresholds are a reason to use the exact product code when reordering.
This comparison covers panel configuration and cutoffs. Verify each product’s labeling and intended-use designation separately before selecting it.
Does an OPI Panel Include Every Opioid?
No. Opiates are part of the broader opioid family, and an opiate immunoassay does not provide universal opioid coverage. ARUP Consult explains that fully synthetic opioids such as fentanyl and methadone require an appropriate testing method.
Check dedicated fentanyl, oxycodone, methadone and buprenorphine assays separately. For example, the 120ml fentanyl cup with MTD and OXY lists these additional targets explicitly. Neither the number 300 nor 2000 adds those panels to another cup.
How to Select and Reorder an Opiate Test Cup
- Confirm the required assay. Identify the drug or drug class your testing procedure specifies.
- Check the cutoff. Record OPI/300 or OPI/2000 along with the other panel requirements.
- Match the exact product. Verify the SKU, labeling and supplied instructions before accepting a substitute.
- Plan result handling. Follow the procedure for invalid screens, unexpected results and appropriate laboratory confirmation.
A preliminary non-negative OPI result should not be treated as proof of impairment or as identification of one particular drug. Our drug test result-reading guide explains the distinction between negative, non-negative and invalid screens.
For supply inquiries, send the required SKU and quantity through our wholesale test supplies page.
Frequently Asked Questions
What does OPI2000 mean on a drug test?
OPI2000 identifies an opiate screening assay with a listed cutoff of 2000 ng/mL. It does not mean the sample contains exactly 2000 ng/mL, and it is not a measure of impairment.
Is OPI 300 more accurate than OPI 2000?
A lower cutoff is not the same as greater overall accuracy. OPI/300 and OPI/2000 use different decision thresholds. Select the assay and cutoff required for the testing purpose.
Does OPI 2000 test for fentanyl?
An OPI/2000 label does not establish fentanyl coverage. Choose a device with a dedicated fentanyl assay when fentanyl screening is required.
Does an OPI result identify the exact drug used?
A preliminary opiate-class result does not by itself identify a specific substance or establish how it entered the specimen. Appropriate laboratory testing and result review are needed when more specific identification is required.
